External lysis of Escherichia coli by a bacteriophage endolysin modified with hydrophobic amino acids

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Lysis of Escherichia coli cells induced by bacteriophage T4.

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Several hypotheses have been proposed to explain the poorly understood mechanism by which virulent bacteriophage induces lysis in bacteria (Hershey and Bronfenbrenner, 1952; Luria, 1953). It has been suggested that lysis is caused by: 1) the accumulation of an overwhelming amount of phage within the cell (d'Herelle, 1926); 2) the possession by the phage of a lytic enzyme (Sertic, 1929; Anderson...

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ژورنال

عنوان ژورنال: AMB Express

سال: 2019

ISSN: 2191-0855

DOI: 10.1186/s13568-019-0838-x